upregulate synonym
The SensagentBox are offered by sensAgent. ;A positive regulatory process that increases ligand-receptor interactions. A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. A synonym for upregulation is modulation. Contact Us We're doing our best to make sure our content is useful, accurate and safe.If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly. A cell's ability to respond to a chemical message depends on the presence of receptors tuned to that message. Tips: browse the semantic fields (see From ideas to words) in two languages to learn more. The disequilibrium caused by these changes often causes withdrawal when the long-term use of a drug is discontinued. Synonyms for 'Upregulated'. The more receptors a cell has that are tuned to the message, the more the cell will respond to it. However, the use of certain receptor antagonists may also damage receptors faster than they upregulate (internalization of receptors due to antagonism). The wordgames anagrams, crossword, Lettris and Boggle are provided by Memodata. Over time, this self-induced loss of target cell receptors for insulin reduces the target cell's sensitivity to the elevated hormone concentration. Synonyms (Other Words) for Upregulate & Antonyms (Opposite Meaning) for Upregulate. Synonyms.com. We truly appreciate your support. Thanks for your vote! The rate of synthesis of new receptors within the endoplasmic reticulum and their insertion in the plasma membrane do not keep pace with their rate of destruction. Get XML access to reach the best products. Top synonyms for upregulated (other words for upregulated) are up-regulated, upregulation and up-regulation. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis. Company Information "upregulate." Elevated levels of the hormone insulin in the blood trigger downregulation of the associated receptors. English thesaurus is mainly derived from The Integral Dictionary (TID). A positive regulatory effect on physiological processes at the molecular, cellular, or systemic levelAt the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. A windows (pop-into) of information (full-content of Sensagent) triggered by double-clicking any word on your webpage. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis. We're doing our best to make sure our content is useful, accurate and safe.If by any chance you spot an inappropriate image within your search results please use this form to let us know, and we'll take care of it shortly.  | Last modifications, Copyright © 2012 sensagent Corporation: Online Encyclopedia, Thesaurus, Dictionary definitions and more. Top 30 analogous words or synonyms for upregulation upregulation downregulation overexpression dysregulation catenin repression apoptosis mapk autophagy hyperactivation knockdown nfb erk akt overproduction upregulated phosphorylation inos tumorigenesis wnt downregulated deregulation pkc tgf jnk rhoa proinflammatory pten enos shh egfr https://www.synonyms.com/synonym/upregulate. STANDS4 LLC, 2020. See if you can get into the grid Hall of Fame ! English Encyclopedia is licensed by Wikipedia (GNU). At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. Downregulation of receptors happens when receptors have been chronically exposed to an excessive amount of neurotransmitters, whether endogenous or drugs. Receptors are created, or expressed, by the DNA of the cell, and they can be increased, or upregulated, when the signal is weak, or decreased, or downregulated, when it is strong. ○   Anagrams All living cells have the ability to receive and process signals that originate outside of their walls, which they do by means of proteins called receptors, usually found on a cell's surface. Letters must be adjacent and longer words score better. The complementary process that involves increases of such components is called. Best synonyms for 'upregulated' are 'positively disposed towards', 'up-regulated' and 'up-regulation'. Find out more. 1. Find more similar words at wordhippo.com! ], Gene Circuits, Gene Module, Gene Modules, Gene Networks, Gene Regulatory Networks, Transcriptional Networks[Analogie], Feedback, Biochemical, Feedback Inhibition, Biochemical, Feedback Regulation, Biochemical, Feedback Stimulation, Biochemical, Negative Feedback, Biochemical, Positive Feedback, Biochemical - Expression Regulation, Gene, Gene Action Regulation, Gene Activation, Gene Expression Regulation, Genetic Induction, Induction, Genetic, Regulation, Gene Action, Regulation, Gene Expression, Regulation of Gene Expression - Chemical and Pharmacologic Phenomena - Biochemical Phenomena, Phenomena, Biochemical[Hyper.]. (adsbygoogle = window.adsbygoogle || []).push({}); Top 10 similar words or synonyms for upregulation, Top 30 analogous words or synonyms for upregulation. An increase of a … ○   Boggle. . Privacy policy Upregulation (n.). With a SensagentBox, visitors to your site can access reliable information on over 5 million pages provided by Sensagent.com. Add new content to your site from Sensagent by XML. Eco, Cookies help us deliver our services. Find all the synonyms and alternative words for upregulate at Synonyms.com, the largest free online thesaurus, antonyms, definitions and translations resource on the web. 1. This results in ligand-induced desensitization or internalization of that receptor. (MeSH)A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. ). Choose the design that fits your site. Most English definitions are provided by WordNet . ;A positive regulatory process that increases ligand-receptor interactions. To make squares disappear and save space for other squares you have to assemble English words (left, right, up, down) from the falling squares. Get XML access to fix the meaning of your metadata. Boggle gives you 3 minutes to find as many words (3 letters or more) as you can in a grid of 16 letters. Synonym of Upregulation: English Wikipedia - The Free Encyclopedia Downregulation and upregulation Downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external variable. Web. Another example can be seen in diabetes insipidus, in which the kidneys become insensitive to arginine vasopressin. Get instant synonyms for any word that hits you anywhere on the web! ○   Wildcard, crossword Change the target language to find translations.  |  It is usually exhibited by various hormone receptors. In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. The web service Alexandria is granted from Memodata for the Ebay search. Give contextual explanation and translation from your sites ! When insulin binds to its receptors on the surface of a cell, the hormone receptor complex undergoes endocytosis and is subsequently attacked by intracellular lysosomal enzymes. At high plasma concentrations, the number of surface receptors for insulin is gradually reduced by the accelerated rate of receptor internalization and degradation brought about by increased hormonal binding. Each square carries a letter. 19 Oct. 2020. All rights reserved. The English word games are: ;A positive regulatory process that increases ligand-receptor interactions. Lettris is a curious tetris-clone game where all the bricks have the same square shape but different content. The internalization of the insulin molecules provides a pathway for degradation of the hormone as well as for regulation of the number of sites that are available for binding on the cell surface. By using our services, you agree to our use of cookies. You can also try the grid of 16 letters. Biochemical Phenomena, Metabolism, and Nutrition, Metabolism, Nutrition, and Biochemical Phenomena, Gene Circuits, Gene Module, Gene Modules, Gene Networks, Gene Regulatory Networks, Transcriptional Networks, Feedback, Biochemical, Feedback Inhibition, Biochemical, Feedback Regulation, Biochemical, Feedback Stimulation, Biochemical, Negative Feedback, Biochemical, Positive Feedback, Biochemical, Expression Regulation, Gene, Gene Action Regulation, Gene Activation, Gene Expression Regulation, Genetic Induction, Induction, Genetic, Regulation, Gene Action, Regulation, Gene Expression, Regulation of Gene Expression, Biochemical Phenomena, Phenomena, Biochemical, an offensive content(racist, pornographic, injurious, etc. When such signals bind to a receptor, they effectively direct the cell to do something, such as dividing, dying, or allowing substances to be created, or to enter or exit the cell. G05.315.850, G06.184.910, G07.621.487.750, G12.955, Receptor Up-Regulation  (MeSH), Up-Regulation  (MeSH), Up-Regulation (Physiology)  (MeSH), Autoregulation, Homeostasis - Genetic Process, Genetic Processes - Biochemical Phenomena, Metabolism, and Nutrition, Metabolism, Nutrition, and Biochemical Phenomena[Hyper. ○   Lettris  |  An example of downregulation is the cellular decrease in the number of receptors to a molecule, such as a hormone or neurotransmitter, which reduces the cell's sensitivity to the molecule. Some receptor agonists may cause downregulation of their respective receptors, while most receptor antagonists temporarily upregulate their respective receptors. This is an example of a locally acting negative feedback mechanism.

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